Properties of Ribosomes from Streptomyces erythreus and Streptomyces griseus

ABBOTT 29119, from Streptomyces erythreus

HUNG, P. P. (Abbott Laboratories, North Chicago, Ill.), C. L. MARKS, AND P. L. TARDREW. Isolation and characterization of a new antibiotic, ABBOTT 29119, from Streptomyces erythreus. Appl. Microbiol. 13:216-317. 1965.-A new antibiotic was isolated from fermentations of Streptomyces erythreus designed for erythromycin A production. Isolation of this compound was accomplished by use of ion-exchan...

Oxidation of Meloxicam by Streptomyces griseus

The aim of the present investigation was to biotransform the anti-inflammatory compound meloxicam by enzymes present in whole cells of five actinomycete cultures to produce novel bioactive derivatives. Among the actinomycetes screened, Streptomyces griseus NCIM 2622 was found to possess the enzyme system(s) that oxidize meloxicam into two metabolites whereas that present in S. griseus NCIM 2623...

Isolation and characterization of a phage active against streptomyces griseus

Glutathione S-transferase isoenzymes from Streptomyces griseus.

An inducible, cytosolic glutathione S-transferase (GST) was purified from Streptomyces griseus. GST isoenzymes with pI values of 6.8 and 7.9 used standard GST substrates including 1-chloro-2,4-dinitrobenzene. GST had subunit and native M(r)s of 24 and 48, respectively, and the N-terminal sequence SMILXYWDIIRGLPAH.

Genetic recombination in Streptomyces griseus.

Low-frequency (10(-6)) genetic recombination was observed in a cephamycin-producing strain of Streptomyces griseus. The recombinants were predominantly heteroclones. Heteroclone analysis was performed involving four heteroclones of one cross. In 100 mutants correlation was found between the type of auxotrophy and the level of antibiotic activity. A cross of this strain with a streptomycin-produ...